Nathan Shock Center
March 18, 2021
Jiyoon Ryu, Jason T Hadley, Zhi Li, Feng Dong, Huan Xu, Xiaoban Xin, Ye Zhang, Cang Chen, Senlin Li, Xiaoning Guo, Jared L Zhao, Robin J Leach, Muhammad A Abdul-Ghani, Ralph A DeFronzo, Amrita Kamat, Feng Liu, Lily Q Dong Diabetes. 2021 Jun;70(6):1303-1316. doi: 10.2337/db20-1073. Epub 2021 Mar 18. Abstract: Adiponectin is an adipokine that […]
March 11, 2021
Dan Tang, Zhao Zhang, Emily Zboril, Michael D Wetzel, Xinping Xu, Wei Zhang, Lizhen Chen, Zhijie Liu J Mol Biol. 2021 Jul 9;433(14):166928. doi: 10.1016/j.jmb.2021.166928. Epub 2021 Mar 11. Abstract: Pontin is a AAA+ ATPase protein that has functions in various biological contexts including gene transcription regulation, chromatin remodeling, DNA damage sensing and repair, as […]
March 9, 2021
Jan Vijg Ageing Res Rev. 2021 Jul:68:101316. doi: 10.1016/j.arr.2021.101316. Epub 2021 Mar 9. Abstract: Damage to the repository of genetic information in cells has plagued life since its very beginning 3-4 billion years ago. Initially, in the absence of an ozone layer, especially damage from solar UV radiation must have been frequent, with other sources, […]
March 2, 2021
Niannian Ji, Neelam Mukherjee, Ryan M Reyes, Jonathan Gelfond, Martin Javors, Joshua J Meeks, David J McConkey, Zhen-Ju Shu, Chethan Ramamurthy, Ryan Dennett, Tyler J Curiel, Robert S Svatek J Immunother Cancer. 2021 Mar;9(3):e001941. doi: 10.1136/jitc-2020-001941. Abstract: Background: Although intravesical BCG is the standard treatment of high-grade non-muscle invasive bladder cancer (NMIBC), response rates remain […]
February 27, 2021
Changfeng Hu, Yu Du, Xiaofen Xu, Haichang Li, Qiao Duan, Zhijun Xie, Chengping Wen, Xianlin Han Metabolites. 2021 Feb 27;11(3):142. doi: 10.3390/metabo11030142. Abstract: Lupus nephritis (LN) is an inflammatory renal disease of patients with systemic lupus erythematosus with lots of immune complexes deposited in kidneys. Accumulated studies have demonstrated the close relationships among dyslipidaemia, inflammation, […]
February 12, 2021
T Jake Samuel, Dalane W Kitzman, Mark J Haykowsky, Bharathi Upadhya, Peter Brubaker, M Benjamin Nelson, W Gregory Hundley, Michael D Nelson Am J Physiol Heart Circ Physiol. 2021 Apr 1;320(4):H1535-H1542. doi: 10.1152/ajpheart.00610.2020. Epub 2021 Feb 12. Abstract: This study tested the hypothesis that early left ventricular (LV) relaxation is impaired in older obese patients […]
January 11, 2021
Anil Kumar, Kumaran Sundaram, Jingyao Mu, Gerald W Dryden, Mukesh K Sriwastva, Chao Lei, Lifeng Zhang, Xiaolan Qiu, Fangyi Xu, Jun Yan, Xiang Zhang, Juw Won Park, Michael L Merchant, Henry C L Bohler, Baomei Wang, Shuangqin Zhang, Chao Qin, Ziying Xu, Xianlin Han, Craig J McClain, Yun Teng, Huang-Ge Zhang Nat Commun. 2021 Jan […]
January 8, 2021
Nighat Noureen, Shaofang Wu, Yingli Lv, Juechen Yang, W K Alfred Yung, Jonathan Gelfond, Xiaojing Wang, Dimpy Koul, Andrew Ludlow, Siyuan Zheng Nat Commun. 2021 Jan 8;12(1):139. doi: 10.1038/s41467-020-20474-9. Abstract: Active telomerase is essential for stem cells and most cancers to maintain telomeres. The enzymatic activity of telomerase is related but not equivalent to the […]
December 31, 2020
Manish Parihar, Sherry G Dodds, Marty Javors, Randy Strong, Paul Hasty, Zelton Dave Sharp Aging Pathobiol Ther. 2020;2(4):187-194. doi: 10.31491/apt.2020.12.039. Epub 2020 Dec 31. Abstract: Background: Apc Min/+ mice model familial adenomatous polyposis (FAP), a disease that causes numerous colon polyps leading to colorectal cancer. We previously showed that chronic treatment of Apc Min/+ females […]
December 23, 2020
Chris E Shannon, Mukundan Ragavan, Juan Pablo Palavicini, Marcel Fourcaudot, Terry M Bakewell, Ivan A Valdez, Iriscilla Ayala, Eunsook S Jin, Muniswamy Madesh, Xianlin Han, Matthew E Merritt, Luke Norton Mol Metab. 2021 Mar:45:101154. doi: 10.1016/j.molmet.2020.101154. Epub 2020 Dec 23. Abstract: Objective: Insulin resistance and altered hepatic mitochondrial function are central features of type 2 […]