Publications

Analysis of monohexosyl alkyl (alkenyl)-acyl glycerol in brain samples by shotgun lipidomics

July 24, 2020

Chunyan Wang, Jianing Wang, Chao Qin, Xianlin Han Anal Chim Acta. 2020 Sep 8:1129:143-149. doi: 10.1016/j.aca.2020.07.016. Epub 2020 Jul 24. Abstract: Lipid species possess very different structures, leading to their very diversified cellular functions in biological systems. Lipidomics represents a powerful technology for deep analysis of hundreds to thousands of intact lipid molecular species. In […]

The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats

July 17, 2020

Mitchell E Allen, Edward Ross Pennington, Justin B Perry, Sahil Dadoo, Marina Makrecka-Kuka, Maija Dambrova, Fatiha Moukdar, Hetal D Patel, Xianlin Han, Grahame K Kidd, Emily K Benson, Tristan B Raisch, Steven Poelzing, David A Brown, Saame Raza Shaikh Commun Biol. 2020 Jul 17;3(1):389. doi: 10.1038/s42003-020-1101-3. Abstract: Mitochondrial dysfunction contributes to cardiac pathologies. Barriers to […]

Pathogenic Tau Causes a Toxic Depletion of Nuclear Calcium

July 14, 2020

Rebekah Mahoney, Elizabeth Ochoa Thomas, Paulino Ramirez, Henry E Miller, Adrian Beckmann, Gabrielle Zuniga, Radek Dobrowolski, Bess Frost. Cell Reports. 2020 Jul 14;32(2):107900. doi: 10.1016/j.celrep.2020.107900. Abstract: Synaptic activity-induced calcium (Ca2+) influx and subsequent propagation into the nucleus is a major way in which synapses communicate with the nucleus to regulate transcriptional programs important for activity-dependent […]