Administrative and Program Enrichment Core Statistical Component
October 31, 2014
Jonathan Gelfond, M.D., Ph.D. The statistical component of the administration core is lead by Dr. Jonathan Gelfond and has contributed to multi-institutional collaborations and has projected its capability to the aging research community through analytical tools. The efforts include an in-depth analysis of rapamycin and caloric restriction effects on the mouse liver transcriptome such as […]
Introducing Our Newest Core: Bioanalytical Pharmacology and Drug Evaluation Core
October 31, 2014
The important and significant discovery in 2009 that the drug rapamycin extended longevity in a mammal (BL6 mice) and that drugs can be used to study mechanisms of aging has required the development of early stage research design procedures to quantify the drug in lab chow, blood, and tissues to confirm the adequate delivery to […]
Examining Various Aspects of Age-related Changes in Physiology in the Naked Mole-Rat
October 31, 2014
Dr. Rochelle Buffenstein of the Aging Animal Models and Longevity Assessment Core and her team have continued to examine various aspects of age-related changes in physiology in the naked mole-rat and within the past 5 years have discovered some significant breakthroughs. Bone quality In this regard we have examined age-related changes in bone quality (Pinto […]